Insulin-Like Growth Factor (IGF-1)

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Insulin

Insulin is peptide hormone produced in the Islets of Langerhans in the pancreas.The release of this hormone in the human body is most closely tied to blood glucose levels, although a number of other factors including pancreatic and gastrointestinal hormones, amino acids, fatty acids, and ketone bodies are also involved. The main biological role of insulin is to promote the intracellular utilization and storage of amino acids, glucose, and fatty acids, while simultaneously inhibiting the breakdown of glycogen, protein, and fat. It is most notably identified with the control of blood sugar levels, and insulin medications are typically prescribed to people with diabetes, a metabolic disorder characterized by hyperglycemia (high blood sugar).While insulin targets many different organs in the body, this hormone is both anabolic and anti-catabolic to skeletal muscle tissue, a fact that explains the inclusion of pharmaceutical insulin in the realm of athletics and bodybuilding

Insulin-Like Growth Factor I (IGF-I)

Insulin-Like Growth Factor I IGF-I is an insulinlike hormone with marked anabolic effects. Owing to its name, it also has some insulin-like effects as well. IGF-I increases protein synthesis, and supports the proliferation and differentiation of satellite cells. The prostaglandin PGF2alpha is known to strongly up-regulate local IGF-I receptor expression.PGE2 is also believed to play a role in increasing local IGF-1 synthesis

Insulin-Like Growth Factor II (IGF-II)

Insulin-Like Growth Factor II (IGF-II): IGF-II is a second insulin-like growth factor that plays a role in the proliferation of satellite cells. Unlike IGF-I, IGF-II expression does not appear to drastically increase in response to training

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